Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells
About this item
Full title
Author / Creator
Chauss, Daniel , Freiwald, Tilo , McGregor, Reuben , Yan, Bingyu , Wang, Luopin , Nova-Lamperti, Estefania , Kumar, Dhaneshwar , Zhang, Zonghao , Teague, Heather , West, Erin E. , Vannella, Kevin M. , Ramos-Benitez, Marcos J. , Bibby, Jack , Kelly, Audrey , Malik, Amna , Freeman, Alexandra F. , Schwartz, Daniella M. , Portilla, Didier , Chertow, Daniel S. , John, Susan , Lavender, Paul , Kemper, Claudia , Lombardi, Giovanna , Mehta, Nehal N. , Cooper, Nichola , Lionakis, Michail S. , Laurence, Arian , Kazemian, Majid and Afzali, Behdad
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The molecular mechanisms governing orderly shutdown and retraction of CD4
+
type 1 helper T (T
H
1) cell responses remain poorly understood. Here we show that complement triggers contraction of T
H
1 responses by inducing intrinsic expression of the vitamin D (VitD) receptor and the VitD-activating enzyme CYP27B1, permitting T cel...
Alternative Titles
Full title
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells
Authors, Artists and Contributors
Author / Creator
Freiwald, Tilo
McGregor, Reuben
Yan, Bingyu
Wang, Luopin
Nova-Lamperti, Estefania
Kumar, Dhaneshwar
Zhang, Zonghao
Teague, Heather
West, Erin E.
Vannella, Kevin M.
Ramos-Benitez, Marcos J.
Bibby, Jack
Kelly, Audrey
Malik, Amna
Freeman, Alexandra F.
Schwartz, Daniella M.
Portilla, Didier
Chertow, Daniel S.
John, Susan
Lavender, Paul
Kemper, Claudia
Lombardi, Giovanna
Mehta, Nehal N.
Cooper, Nichola
Lionakis, Michail S.
Laurence, Arian
Kazemian, Majid
Afzali, Behdad
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612139
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612139
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-01080-3
