Genome-wide interaction study with major depression identifies novel variants associated with cognit...
Genome-wide interaction study with major depression identifies novel variants associated with cognitive function
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Author / Creator
Thalamuthu, Anbupalam , Mills, Natalie T. , Berger, Klaus , Minnerup, Heike , Grotegerd, Dominik , Dannlowski, Udo , Meinert, Susanne , Opel, Nils , Repple, Jonathan , Gruber, Marius , Nenadić, Igor , Stein, Frederike , Brosch, Katharina , Meller, Tina , Pfarr, Julia-Katharina , Forstner, Andreas J. , Hoffmann, Per , Nöthen, Markus M. , Witt, Stephanie , Rietschel, Marcella , Kircher, Tilo , Adams, Mark , McIntosh, Andrew M. , Porteous, David J. , Deary, Ian J. , Hayward, Caroline , Campbell, Archie , Grabe, Hans Jörgen , Teumer, Alexander , Homuth, Georg , van der Auwera-Palitschka, Sandra , Schubert, K. Oliver and Baune, Bernhard T.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Major Depressive Disorder (MDD) often is associated with significant cognitive dysfunction. We conducted a meta-analysis of genome-wide interaction of MDD and cognitive function using data from four large European cohorts in a total of 3510 MDD cases and 6057 controls. In addition, we conducted analyses using polygenic risk scores (PRS) based on da...
Alternative Titles
Full title
Genome-wide interaction study with major depression identifies novel variants associated with cognitive function
Authors, Artists and Contributors
Author / Creator
Mills, Natalie T.
Berger, Klaus
Minnerup, Heike
Grotegerd, Dominik
Dannlowski, Udo
Meinert, Susanne
Opel, Nils
Repple, Jonathan
Gruber, Marius
Nenadić, Igor
Stein, Frederike
Brosch, Katharina
Meller, Tina
Pfarr, Julia-Katharina
Forstner, Andreas J.
Hoffmann, Per
Nöthen, Markus M.
Witt, Stephanie
Rietschel, Marcella
Kircher, Tilo
Adams, Mark
McIntosh, Andrew M.
Porteous, David J.
Deary, Ian J.
Hayward, Caroline
Campbell, Archie
Grabe, Hans Jörgen
Teumer, Alexander
Homuth, Georg
van der Auwera-Palitschka, Sandra
Schubert, K. Oliver
Baune, Bernhard T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612684
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612684
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-021-01379-5
