Opioid antagonism in humans: a primer on optimal dose and timing for central mu-opioid receptor bloc...
Opioid antagonism in humans: a primer on optimal dose and timing for central mu-opioid receptor blockade
About this item
Full title
Author / Creator
Publisher
England: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
England: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Non-human animal studies outline precise mechanisms of central mu-opioid regulation of pain, stress, affiliation and reward processing. In humans, pharmacological blockade with non-selective opioid antagonists such as naloxone and naltrexone is typically used to assess involvement of the mu-opioid system in such processing. However, robust estimate...
Alternative Titles
Full title
Opioid antagonism in humans: a primer on optimal dose and timing for central mu-opioid receptor blockade
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7613944
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7613944
Other Identifiers
ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-022-01416-z
