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Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats

Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7646993

Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats

About this item

Full title

Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats

Publisher

Greece: Spandidos Publications

Journal title

Molecular medicine reports, 2020-12, Vol.22 (6), p.5271-5281

Language

English

Formats

Publication information

Publisher

Greece: Spandidos Publications

More information

Scope and Contents

Contents

Arsenic trioxide (ATO) is commonly used to treat patients with acute promyelocytic leukemia since it was authorized by the U.S. Food and Drug Administration in the 1970s, but its applicability has been limited by its cardiotoxic effects. Therefore, the aim of the present study was to investigate the cardioprotective effects and underlying mechanism...

Alternative Titles

Full title

Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7646993

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7646993

Other Identifiers

ISSN

1791-2997

E-ISSN

1791-3004

DOI

10.3892/mmr.2020.11587

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