Complement C6 deficiency exacerbates pathophysiology after spinal cord injury
Complement C6 deficiency exacerbates pathophysiology after spinal cord injury
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Historically, the membrane attack complex, composed of complement components C5b-9, has been connected to lytic cell death and implicated in secondary injury after a CNS insult. However, studies to date have utilized either non-littermate control rat models, or mouse models that lack significant C5b-9 activity. To investigate what role C5b-9 plays...
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Complement C6 deficiency exacerbates pathophysiology after spinal cord injury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7659012
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7659012
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-76441-3