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Complement C6 deficiency exacerbates pathophysiology after spinal cord injury

Complement C6 deficiency exacerbates pathophysiology after spinal cord injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7659012

Complement C6 deficiency exacerbates pathophysiology after spinal cord injury

About this item

Full title

Complement C6 deficiency exacerbates pathophysiology after spinal cord injury

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-11, Vol.10 (1), p.19500-19500, Article 19500

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Historically, the membrane attack complex, composed of complement components C5b-9, has been connected to lytic cell death and implicated in secondary injury after a CNS insult. However, studies to date have utilized either non-littermate control rat models, or mouse models that lack significant C5b-9 activity. To investigate what role C5b-9 plays...

Alternative Titles

Full title

Complement C6 deficiency exacerbates pathophysiology after spinal cord injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7659012

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7659012

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-76441-3

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