From Suppressor T Cells to Regulatory T Cells: How the Journey that Began with the Discovery of the...
From Suppressor T Cells to Regulatory T Cells: How the Journey that Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Aryl hydrocarbon receptor (AhR) was identified in the early 1970s as a receptor for the ubiquitous environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin), which is a member of halogenated aromatic hydrocarbons (HAHs). TCDD was found to be highly toxic to the immune system, causing thymic involution and suppression of a variety...
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Full title
From Suppressor T Cells to Regulatory T Cells: How the Journey that Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7660163
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7660163
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms21217849
