Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination
Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Diacylglycerol kinase γ (DGKγ) is a lipid kinase to convert diacylglycerol (DG) to phosphatidic acid (PA) and indirectly regulates protein kinase C γ (PKCγ) activity. We previously reported that the basal PKCγ upregulation impairs cerebellar long-term depression (LTD) in the conventional DGKγ knockout (KO) mice. However, the precise mechanism in im...
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Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7660329
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7660329
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms21217866