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Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination

Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7660329

Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination

About this item

Full title

Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2020-11, Vol.21 (21), p.7866

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Diacylglycerol kinase γ (DGKγ) is a lipid kinase to convert diacylglycerol (DG) to phosphatidic acid (PA) and indirectly regulates protein kinase C γ (PKCγ) activity. We previously reported that the basal PKCγ upregulation impairs cerebellar long-term depression (LTD) in the conventional DGKγ knockout (KO) mice. However, the precise mechanism in im...

Alternative Titles

Full title

Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7660329

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7660329

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms21217866

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