Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pan...
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells
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Author / Creator
Fang, Zijian , Chen, Shiqian , Manchanda, Yusman , Bitsi, Stavroula , Pickford, Philip , David, Alessia , Shchepinova, Maria M , Corrêa, Jr, Ivan R , Hodson, David J , Broichhagen, Johannes , Tate, Edward W , Reimann, Frank , Salem, Victoria , Rutter, Guy A , Tan, Tricia , Bloom, Stephen R , Tomas, Alejandra and Jones, Ben
Publisher
Switzerland: MDPI
Journal title
Language
English
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Publisher
Switzerland: MDPI
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Contents
The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of blood glucose homeostasis. Ligand-specific differences in membrane trafficking of the GLP-1R influence its signalling properties and therapeutic potential in type 2 diabetes. Here, we have evaluated how different factors combine to control the post-endocytic trafficking of G...
Alternative Titles
Full title
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7664906
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7664906
Other Identifiers
ISSN
1422-0067
E-ISSN
1422-0067
DOI
10.3390/ijms21218404
