Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank...
Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort
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Publisher
England: Oxford University Press
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Language
English
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Publisher
England: Oxford University Press
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Scope and Contents
Contents
The HLA genes, the most polymorphic genes in the human genome, constitute the strongest single genetic susceptibility factor for autoimmune diseases, transplantation alloimmunity and infections. HLA imputation via statistical inference of alleles based on single-nucleotide polymorphisms (SNPs) in linkage disequilibrium (LD) with alleles is a powerf...
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Full title
Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7671345
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7671345
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ISSN
2631-9268
E-ISSN
2631-9268
DOI
10.1093/nargab/lqaa030