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Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank...

Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7671345

Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort

About this item

Full title

Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort

Publisher

England: Oxford University Press

Journal title

NAR genomics and bioinformatics, 2020-06, Vol.2 (2), p.lqaa030-lqaa030

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

The HLA genes, the most polymorphic genes in the human genome, constitute the strongest single genetic susceptibility factor for autoimmune diseases, transplantation alloimmunity and infections. HLA imputation via statistical inference of alleles based on single-nucleotide polymorphisms (SNPs) in linkage disequilibrium (LD) with alleles is a powerf...

Alternative Titles

Full title

Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7671345

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7671345

Other Identifiers

ISSN

2631-9268

E-ISSN

2631-9268

DOI

10.1093/nargab/lqaa030

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