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Patulin suppresses α1-adrenergic receptor expression in HEK293 cells

Patulin suppresses α1-adrenergic receptor expression in HEK293 cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7674415

Patulin suppresses α1-adrenergic receptor expression in HEK293 cells

About this item

Full title

Patulin suppresses α1-adrenergic receptor expression in HEK293 cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-11, Vol.10 (1), Article 20115

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Patulin (PAT) is a common mycotoxin contaminant of apple products linked to impaired metabolic and kidney function. Adenosine monophosphate activated protein kinase (AMPK), abundantly expressed in the kidney, intercedes metabolic changes and renal injury. The alpha-1-adrenergic receptors (α
1
-AR) facilitate Epinephrine (Epi)-mediated AMPK ac...

Alternative Titles

Full title

Patulin suppresses α1-adrenergic receptor expression in HEK293 cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7674415

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7674415

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-77157-0

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