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Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7677226

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

About this item

Full title

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

Publisher

London: Nature Publishing Group UK

Journal title

Nature microbiology, 2020-12, Vol.5 (12), p.1490-1503

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cells infected by influenza virus mount a large-scale antiviral response and most cells ultimately initiate cell-death pathways in an attempt to suppress viral replication. We performed a CRISPR–Cas9-knockout selection designed to identify host factors required for replication after viral entry. We identified a large class of presumptive antiviral...

Alternative Titles

Full title

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7677226

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7677226

Other Identifiers

ISSN

2058-5276

E-ISSN

2058-5276

DOI

10.1038/s41564-020-0778-x

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