Inflammasomes and Childhood Autoimmune Diseases: A Review of Current Knowledge
Inflammasomes and Childhood Autoimmune Diseases: A Review of Current Knowledge
About this item
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Author / Creator
Publisher
New York: Springer US
Journal title
Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Inflammasomes are multiprotein complexes capable of sensing pathogen-associated molecular patterns (PAMPs), danger-associated molecular patterns (DAMPs), and cellular perturbations. Upon stimulation, the inflammasomes activate the production of the pro-inflammatory cytokines IL-1β and IL-18 and induce gasdermin D-mediated pyroptosis. Dysregulated i...
Alternative Titles
Full title
Inflammasomes and Childhood Autoimmune Diseases: A Review of Current Knowledge
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7685913
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7685913
Other Identifiers
ISSN
1080-0549
E-ISSN
1559-0267
DOI
10.1007/s12016-020-08825-2
