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Toll-Like Receptor 3 in Solid Cancer and Therapy Resistance

Toll-Like Receptor 3 in Solid Cancer and Therapy Resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7692054

Toll-Like Receptor 3 in Solid Cancer and Therapy Resistance

About this item

Full title

Toll-Like Receptor 3 in Solid Cancer and Therapy Resistance

Publisher

MDPI AG

Journal title

Cancers, 2020-11, Vol.12 (11), p.3227

Language

English

Formats

Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

Toll-like receptor 3 (TLR3) is a member of the TLR family, which has been extensively studied for its antiviral function. It is highly expressed in the endosomes of antigen-presenting immune cells and epithelial cells. TLR3 binds specifically double-strand RNAs (dsRNAs), leading to the activation of mainly two downstream pathways: the phosphorylati...

Alternative Titles

Full title

Toll-Like Receptor 3 in Solid Cancer and Therapy Resistance

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7692054

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7692054

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers12113227

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