Role of POLE and POLD1 in familial cancer
Role of POLE and POLD1 in familial cancer
About this item
Full title
Author / Creator
Mur, Pilar , García-Mulero, Sandra , del Valle, Jesús , Magraner-Pardo, Lorena , Vidal, August , Pineda, Marta , Cinnirella, Giacomo , Martín-Ramos, Edgar , Pons, Tirso , López-Doriga, Adriana , Belhadj, Sami , Feliubadaló, Lidia , Munoz-Torres, Pau M. , Navarro, Matilde , Grau, Elia , Darder, Esther , Llort, Gemma , Sanz, Judit , Ramón y Cajal, Teresa , Balmana, Judith , Brunet, Joan , Moreno, Victor , Piulats, Josep M. , Matías-Guiu, Xavier , Sanz-Pamplona, Rebeca , Aligué, Rosa , Capellá, Gabriel , Lázaro, Conxi and Valle, Laura
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Purpose
Germline pathogenic variants in the exonuclease domain (ED) of polymerases
POLE
and
POLD1
predispose to adenomatous polyps, colorectal cancer (CRC), endometrial tumors, and other malignancies, and exhibit increased mutation rate and highly specific associated mutational signatures. The tumor spectrum and prevalence of
POLE...
Alternative Titles
Full title
Role of POLE and POLD1 in familial cancer
Authors, Artists and Contributors
Author / Creator
García-Mulero, Sandra
del Valle, Jesús
Magraner-Pardo, Lorena
Vidal, August
Pineda, Marta
Cinnirella, Giacomo
Martín-Ramos, Edgar
Pons, Tirso
López-Doriga, Adriana
Belhadj, Sami
Feliubadaló, Lidia
Munoz-Torres, Pau M.
Navarro, Matilde
Grau, Elia
Darder, Esther
Llort, Gemma
Sanz, Judit
Ramón y Cajal, Teresa
Balmana, Judith
Brunet, Joan
Moreno, Victor
Piulats, Josep M.
Matías-Guiu, Xavier
Sanz-Pamplona, Rebeca
Aligué, Rosa
Capellá, Gabriel
Lázaro, Conxi
Valle, Laura
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7708298
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7708298
Other Identifiers
ISSN
1098-3600
E-ISSN
1530-0366
DOI
10.1038/s41436-020-0922-2
