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The sodium–glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progress...

The sodium–glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progress...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7714078

The sodium–glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progression in type 2 diabetic mice

About this item

Full title

The sodium–glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progression in type 2 diabetic mice

Publisher

England: John Wiley & Sons, Inc

Journal title

FEBS open bio, 2020-12, Vol.10 (12), p.2761-2770

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Tofogliflozin may prevent glomerular (enlarged mesangial area, foot process effacement, podocyte loss) and tubulointerstitial damage (increased expression of MCP‐1 and KIM‐1), partly by ameliorating hyperglycemia, renal inflammation, and abnormal mitochondrial morphology.
Trials on cardiovascular and renal outcomes in patients with type 2 diabet...

Alternative Titles

Full title

The sodium–glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progression in type 2 diabetic mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7714078

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7714078

Other Identifiers

ISSN

2211-5463

E-ISSN

2211-5463

DOI

10.1002/2211-5463.13014

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