Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis
Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Myasthenia gravis (MG) is a neuromuscular, autoimmune disease caused by autoantibodies that target postsynaptic proteins, primarily the acetylcholine receptor (AChR) and inhibit signaling at the neuromuscular junction. The majority of patients under 50 y with AChR autoantibody MG have thymic lymphofollicular hyperplasia. The MG thymus is a reservoi...
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Full title
Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7720237
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7720237
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2007206117