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Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively...

Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7721244

Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively intact individuals

About this item

Full title

Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively intact individuals

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

Human brain mapping, 2021-01, Vol.42 (1), p.47-64

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The ε4 allele of the gene Apolipoprotein E is the major genetic risk factor for Alzheimer's Disease. APOE ε4 has been associated with changes in brain structure in cognitively impaired and unimpaired subjects, including atrophy of the hippocampus, which is one of the brain structures that is early affected by AD. In this work we analyzed the impact...

Alternative Titles

Full title

Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively intact individuals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7721244

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7721244

Other Identifiers

ISSN

1065-9471,1097-0193

E-ISSN

1097-0193

DOI

10.1002/hbm.25202

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