Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure
Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure
About this item
Full title
Author / Creator
Hughes, Timothy P , Mauro, Michael J , Cortes, Jorge E , Minami, Hironobu , Rea, Delphine , DeAngelo, Daniel J , Breccia, Massimo , Goh, Yeow-Tee , Talpaz, Moshe , Hochhaus, Andreas , le Coutre, Philipp , Ottmann, Oliver , Heinrich, Michael C , Steegmann, Juan L , Deininger, Michael W.N , Janssen, Jeroen J.W.M , Mahon, Francois-Xavier , Minami, Yosuke , Yeung, David , Ross, David M , Tallman, Martin S , Park, Jae H , Druker, Brian J , Hynds, David , Duan, Yuyan , Meille, Christophe , Hourcade-Potelleret, Florence , Vanasse, K. Gary , Lang, Fabian and Kim, Dong-Wook
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Asciminib, a novel ABL tyrosine kinase inhibitor that targets the myristoyl site of the molecule rather than the ATP-binding domain, showed mainly low-grade toxic effects in a minority of patients and considerable antileukemic activity in the majority of those who had resistance to or unacceptable side effects from standard TKIs.
Alternative Titles
Full title
Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure
Authors, Artists and Contributors
Author / Creator
Mauro, Michael J
Cortes, Jorge E
Minami, Hironobu
Rea, Delphine
DeAngelo, Daniel J
Breccia, Massimo
Goh, Yeow-Tee
Talpaz, Moshe
Hochhaus, Andreas
le Coutre, Philipp
Ottmann, Oliver
Heinrich, Michael C
Steegmann, Juan L
Deininger, Michael W.N
Janssen, Jeroen J.W.M
Mahon, Francois-Xavier
Minami, Yosuke
Yeung, David
Ross, David M
Tallman, Martin S
Park, Jae H
Druker, Brian J
Hynds, David
Duan, Yuyan
Meille, Christophe
Hourcade-Potelleret, Florence
Vanasse, K. Gary
Lang, Fabian
Kim, Dong-Wook
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7724923
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7724923
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1902328
