Dichotomous engagement of HDAC3 activity governs inflammatory responses
Dichotomous engagement of HDAC3 activity governs inflammatory responses
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The histone deacetylases (HDACs) are a superfamily of chromatin-modifying enzymes that silence transcription through the modification of histones. Among them, HDAC3 is unique in that interaction with nuclear receptor corepressors 1 and 2 (NCoR1/2) is required to engage its catalytic activity
1
–
3
. However, global loss of HDAC3 also re...
Alternative Titles
Full title
Dichotomous engagement of HDAC3 activity governs inflammatory responses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7725280
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7725280
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2576-2
