Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction
Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Leucine-rich repeat kinase 2 (
LRRK2
) is the most commonly mutated gene in familial Parkinson’s disease
1
and is also linked to its idiopathic form
2
. LRRK2 has been proposed to function in membrane trafficking
3
and colocalizes with microtubules
4
. Despite the fundamental importance of LRRK2 for understanding and t...
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Full title
Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7726071
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7726071
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2673-2