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Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7726071

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

About this item

Full title

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-12, Vol.588 (7837), p.344-349

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Leucine-rich repeat kinase 2 (
LRRK2
) is the most commonly mutated gene in familial Parkinson’s disease
1
and is also linked to its idiopathic form
2
. LRRK2 has been proposed to function in membrane trafficking
3
and colocalizes with microtubules
4
. Despite the fundamental importance of LRRK2 for understanding and t...

Alternative Titles

Full title

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7726071

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7726071

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2673-2

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