Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome
Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome
About this item
Full title
Author / Creator
Zhong, Cheng , Kayamori, Kensuke , Koide, Shuhei , Shinoda, Daisuke , Oshima, Motohiko , Nakajima‐Takagi, Yaeko , Nagai, Yurie , Mimura, Naoya , Sakaida, Emiko , Yamazaki, Satoshi , Iwano, Satoshi , Miyawaki, Atsushi , Ito, Ryoji , Tohyama, Kaoru , Yamaguchi, Kiyoshi , Furukawa, Yoichi , Lennox, William , Sheedy, Josephine , Weetall, Marla and Iwama, Atsushi
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Monomer tubulin polymerize into microtubules, which are highly dynamic and play a critical role in mitosis. Therefore, microtubule dynamics are an important target for anticancer drugs. The inhibition of tubulin polymerization or depolymerization was previously targeted and exhibited efficacy against solid tumors. The novel small molecule PTC596 di...
Alternative Titles
Full title
Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome
Authors, Artists and Contributors
Author / Creator
Kayamori, Kensuke
Koide, Shuhei
Shinoda, Daisuke
Oshima, Motohiko
Nakajima‐Takagi, Yaeko
Nagai, Yurie
Mimura, Naoya
Sakaida, Emiko
Yamazaki, Satoshi
Iwano, Satoshi
Miyawaki, Atsushi
Ito, Ryoji
Tohyama, Kaoru
Yamaguchi, Kiyoshi
Furukawa, Yoichi
Lennox, William
Sheedy, Josephine
Weetall, Marla
Iwama, Atsushi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7734154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7734154
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.14684
