B cell depletion therapies in autoimmune disease: advances and mechanistic insights
B cell depletion therapies in autoimmune disease: advances and mechanistic insights
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather active participants in autoimmune aetiology. This has been fuelled in part by the clinical success of B cell depletion therapies (BCDTs). Originally conceived as a method of eliminating cancerous B cells, BCDTs such as those targeting CD20, CD19 and BAFF are...
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B cell depletion therapies in autoimmune disease: advances and mechanistic insights
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7737718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7737718
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ISSN
1474-1776,1474-1784
E-ISSN
1474-1784
DOI
10.1038/s41573-020-00092-2
