Tofacitinib restores the balance of γδTreg/γδT17 cells in rheumatoid arthritis by inhibiting the NLR...
Tofacitinib restores the balance of γδTreg/γδT17 cells in rheumatoid arthritis by inhibiting the NLRP3 inflammasome
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Author / Creator
Yang, Xinyu , Zhan, Ning , Jin, Yang , Ling, Hanzhi , Xiao, Chipeng , Xie, Zhen , Zhong, Hao , Yu, Xinxin , Tang, Runhua , Ma, Jinglan , Guan, Jubo , Yin, Guoyu , Wu, Gan , Lu, Liangjing and Wang, Jianguang
Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publication information
Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Scope and Contents
Contents
Tofacitinib (TOF) is a Janus kinase (JAK) inhibitor used in the treatment of rheumatoid arthritis (RA), but the mechanism of its action remains unclear. In this study, we investigated the influence of TOF on gamma delta regulatory T-cell (γδTreg)/γδT17 cell balance in RA and the role of the nucleotide-binding domain (NOD)-like receptor protein 3 (N...
Alternative Titles
Full title
Tofacitinib restores the balance of γδTreg/γδT17 cells in rheumatoid arthritis by inhibiting the NLRP3 inflammasome
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7738886
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7738886
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.47860
