Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19
About this item
Full title
Author / Creator
Kalil, Andre C , Patterson, Thomas F , Mehta, Aneesh K , Tomashek, Kay M , Wolfe, Cameron R , Ghazaryan, Varduhi , Marconi, Vincent C , Ruiz-Palacios, Guillermo M , Hsieh, Lanny , Kline, Susan , Tapson, Victor , Iovine, Nicole M , Jain, Mamta K , Sweeney, Daniel A , El Sahly, Hana M , Branche, Angela R , Regalado Pineda, Justino , Lye, David C , Sandkovsky, Uriel , Luetkemeyer, Anne F , Cohen, Stuart H , Finberg, Robert W , Jackson, Patrick E.H , Taiwo, Babafemi , Paules, Catharine I , Arguinchona, Henry , Erdmann, Nathaniel , Ahuja, Neera , Frank, Maria , Oh, Myoung-don , Kim, Eu-Suk , Tan, Seow Y , Mularski, Richard A , Nielsen, Henrik , Ponce, Philip O , Taylor, Barbara S , Larson, LuAnn , Rouphael, Nadine G , Saklawi, Youssef , Cantos, Valeria D , Ko, Emily R , Engemann, John J , Amin, Alpesh N , Watanabe, Miki , Billings, Joanne , Elie, Marie-Carmelle , Davey, Richard T , Burgess, Timothy H , Ferreira, Jennifer , Green, Michelle , Makowski, Mat , Cardoso, Anabela , de Bono, Stephanie , Bonnett, Tyler , Proschan, Michael , Deye, Gregory A , Dempsey, Walla , Nayak, Seema U , Dodd, Lori E , Beigel, John H and ACTT-2 Study Group Members
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a trial involving 1033 patients hospitalized with Covid-19, the addition of baricitinib to remdesivir was associated with shorter recovery time, particularly among patients receiving high-flow oxygen, and with a 30% higher odds of improvement at day 15 than remdesivir alone. Adverse events were less frequent with the combination therapy.
Alternative Titles
Full title
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19
Authors, Artists and Contributors
Author / Creator
Patterson, Thomas F
Mehta, Aneesh K
Tomashek, Kay M
Wolfe, Cameron R
Ghazaryan, Varduhi
Marconi, Vincent C
Ruiz-Palacios, Guillermo M
Hsieh, Lanny
Kline, Susan
Tapson, Victor
Iovine, Nicole M
Jain, Mamta K
Sweeney, Daniel A
El Sahly, Hana M
Branche, Angela R
Regalado Pineda, Justino
Lye, David C
Sandkovsky, Uriel
Luetkemeyer, Anne F
Cohen, Stuart H
Finberg, Robert W
Jackson, Patrick E.H
Taiwo, Babafemi
Paules, Catharine I
Arguinchona, Henry
Erdmann, Nathaniel
Ahuja, Neera
Frank, Maria
Oh, Myoung-don
Kim, Eu-Suk
Tan, Seow Y
Mularski, Richard A
Nielsen, Henrik
Ponce, Philip O
Taylor, Barbara S
Larson, LuAnn
Rouphael, Nadine G
Saklawi, Youssef
Cantos, Valeria D
Ko, Emily R
Engemann, John J
Amin, Alpesh N
Watanabe, Miki
Billings, Joanne
Elie, Marie-Carmelle
Davey, Richard T
Burgess, Timothy H
Ferreira, Jennifer
Green, Michelle
Makowski, Mat
Cardoso, Anabela
de Bono, Stephanie
Bonnett, Tyler
Proschan, Michael
Deye, Gregory A
Dempsey, Walla
Nayak, Seema U
Dodd, Lori E
Beigel, John H
ACTT-2 Study Group Members
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7745180
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7745180
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2031994
