Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinoma...
Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas
About this item
Full title
Author / Creator
Amoedo, Nivea Dias , Sarlak, Saharnaz , Obre, Emilie , Esteves, Pauline , Bégueret, Hugues , Kieffer, Yann , Rousseau, Benoît , Dupis, Alexis , Izotte, Julien , Bellance, Nadège , Dard, Laetitia , Redonnet-Vernhet, Isabelle , Punzi, Giuseppe , Rodrigues, Mariana Figueiredo , Dumon, Elodie , Mafhouf, Walid , Guyonnet-Dupérat, Véronique , Gales, Lara , Palama, Tony , Bellvert, Floriant , Dugot-Senan, Nathalie , Claverol, Stéphane , Baste, Jean-Marc , Lacombe, Didier , Rezvani, Hamid Reza , Pierri, Ciro Leonardo , Mechta-Grigoriou, Fatima , Thumerel, Matthieu and Rossignol, Rodrigue
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Metabolic reprogramming is a common hallmark of cancer, but a large variability in tumor bioenergetics exists between patients. Using high-resolution respirometry on fresh biopsies of human lung adenocarcinoma, we identified 2 subgroups reflected in the histologically normal, paired, cancer-adjacent tissue: high (OX+) mitochondrial respiration and...
Alternative Titles
Full title
Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas
Authors, Artists and Contributors
Author / Creator
Sarlak, Saharnaz
Obre, Emilie
Esteves, Pauline
Bégueret, Hugues
Kieffer, Yann
Rousseau, Benoît
Dupis, Alexis
Izotte, Julien
Bellance, Nadège
Dard, Laetitia
Redonnet-Vernhet, Isabelle
Punzi, Giuseppe
Rodrigues, Mariana Figueiredo
Dumon, Elodie
Mafhouf, Walid
Guyonnet-Dupérat, Véronique
Gales, Lara
Palama, Tony
Bellvert, Floriant
Dugot-Senan, Nathalie
Claverol, Stéphane
Baste, Jean-Marc
Lacombe, Didier
Rezvani, Hamid Reza
Pierri, Ciro Leonardo
Mechta-Grigoriou, Fatima
Thumerel, Matthieu
Rossignol, Rodrigue
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7773363
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7773363
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI133081
