Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development
Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development
About this item
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Author / Creator
Song, Kai , Cai, Xiaofeng , Dong, Yunzhou , Wu, Hao , Wei, Yong , Shankavaram, Uma T , Cui, Kui , Lee, Yang , Zhu, Bo , Bhattacharjee, Sudarshan , Wang, Beibei , Zhang, Kun , Wen, Aiyun , Wong, Scott , Yu, Lili , Xia, Lijun , Welm, Alana L , Bielenberg, Diane R , Camphausen, Kevin A , Kang, Yibin and Chen, Hong
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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More information
Scope and Contents
Contents
Estrogen receptor-negative (ER-negative) breast cancer is thought to be more malignant and devastating than ER-positive breast cancer. ER-negative breast cancer exhibits elevated NF-κB activity, but how this abnormally high NF-κB activity is maintained is poorly understood. The importance of linear ubiquitination, which is generated by the linear u...
Alternative Titles
Full title
Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7773373
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7773373
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI129374
