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An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and di...

An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and di...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7777036

An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease

About this item

Full title

An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (52), p.33507-33518

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Streptococcus pneumoniae (Spn) colonizes the nasopharynx and can cause pneumonia. From the lungs it spreads to the bloodstream and causes organ damage. We characterized the in vivo Spn and mouse transcriptomes within the nasopharynx, lungs, blood, heart, and kidneys using three Spn strains. We identified Spn genes highly expressed at all anatomical...

Alternative Titles

Full title

An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7777036

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7777036

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2010428117

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