Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of cli...
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy
About this item
Full title
Author / Creator
Lv, Mengze , Chen, Meixia , Zhang, Rui , Zhang, Wen , Wang, Chenguang , Zhang, Yan , Wei, Xiaoming , Guan, Yukun , Liu, Jiejie , Feng, Kaichao , Jing, Miao , Wang, Xurui , Liu, Yun-Cai , Mei, Qian , Han, Weidong and Jiang, Zhengfan
Publisher
Singapore: Springer Singapore
Journal title
Language
English
Formats
Publication information
Publisher
Singapore: Springer Singapore
Subjects
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Scope and Contents
Contents
CD8
+
T cell-mediated cancer clearance is often suppressed by the interaction between inhibitory molecules like PD-1 and PD-L1, an interaction acts like brakes to prevent T cell overreaction under normal conditions but is exploited by tumor cells to escape the immune surveillance. Immune checkpoint inhibitors have revolutionized cancer therap...
Alternative Titles
Full title
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7785004
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7785004
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-020-00395-4
