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Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7792585

Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

About this item

Full title

Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

Publisher

Switzerland: MDPI

Journal title

International journal of molecular sciences, 2020-12, Vol.22 (1), p.22

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

The muscarinic receptor antagonist trospium chloride (TCl) is used for pharmacotherapy of the overactive bladder syndrome. TCl is a hydrophilic positively charged drug. Therefore, it has low permeability through biomembranes and requires drug transporters for distribution and excretion. In humans, the organic cation transporters OCT1 and OCT2 and t...

Alternative Titles

Full title

Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7792585

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7792585

Other Identifiers

ISSN

1422-0067

E-ISSN

1422-0067

DOI

10.3390/ijms22010022

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