Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
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Publisher
Switzerland: MDPI
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Language
English
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Publisher
Switzerland: MDPI
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Scope and Contents
Contents
The muscarinic receptor antagonist trospium chloride (TCl) is used for pharmacotherapy of the overactive bladder syndrome. TCl is a hydrophilic positively charged drug. Therefore, it has low permeability through biomembranes and requires drug transporters for distribution and excretion. In humans, the organic cation transporters OCT1 and OCT2 and t...
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Full title
Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7792585
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7792585
Other Identifiers
ISSN
1422-0067
E-ISSN
1422-0067
DOI
10.3390/ijms22010022