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Coenzyme Q Depletion Reshapes MCF-7 Cells Metabolism

Coenzyme Q Depletion Reshapes MCF-7 Cells Metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7795339

Coenzyme Q Depletion Reshapes MCF-7 Cells Metabolism

About this item

Full title

Coenzyme Q Depletion Reshapes MCF-7 Cells Metabolism

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2020-12, Vol.22 (1), p.198

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Mitochondrial dysfunction plays a significant role in the metabolic flexibility of cancer cells. This study aimed to investigate the metabolic alterations due to Coenzyme Q depletion in MCF-7 cells. Method: The Coenzyme Q depletion was induced by competitively inhibiting with 4-nitrobenzoate the coq2 enzyme, which catalyzes one of the final reactio...

Alternative Titles

Full title

Coenzyme Q Depletion Reshapes MCF-7 Cells Metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7795339

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7795339

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms22010198

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