Genetic screening for single-cell variability modulators driving therapy resistance
Genetic screening for single-cell variability modulators driving therapy resistance
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Cellular plasticity describes the ability of cells to transition from one set of phenotypes to another. In melanoma, transient fluctuations in the molecular state of tumor cells mark the formation of rare cells primed to survive BRAF inhibition and reprogram into a stably drug-resistant fate. However, the biological processes governing cellular pri...
Alternative Titles
Full title
Genetic screening for single-cell variability modulators driving therapy resistance
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7796998
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7796998
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-020-00749-z
