Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney
Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney
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England: Wiley Subscription Services, Inc
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Language
English
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England: Wiley Subscription Services, Inc
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Contents
Hypomagnesaemia is a common feature of renal Na+ wasting disorders such as Gitelman and EAST/SeSAME syndrome. These genetic defects specifically affect Na+ reabsorption in the distal convoluted tubule, where Mg2+ reabsorption is tightly regulated. Apical uptake via TRPM6 Mg2+ channels and basolateral Mg2+ extrusion via a putative Na+‐Mg2+ exchanger...
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Full title
Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7816272
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7816272
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ISSN
1748-1708,1748-1716
E-ISSN
1748-1716
DOI
10.1111/apha.13528
