ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in ca...
ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in cancer
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Cisplatin is a mainstay of systemic therapy for a variety of cancers, such as lung cancer, head and neck cancer, and ovarian cancer. However, resistance to cisplatin represents one of themost significant barriers for patient outcome improvement. Actin-like 6A (ACTL6A) is a component of several chromatin remodeling complexes, including SWI/SNF, NuA4...
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ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7826354
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7826354
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2015808118