Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidat...
Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Background
Glutamine (Gln) is an abundant nutrient used by cancer cells. Breast cancers cells and particularly triple-receptor negative breast cancer (TNBC) are reported to be dependent on Gln to produce the energy required for survival and proliferation. Despite intense research on the role of the intracellular Gln pathway, few reports have foc...
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Full title
Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7852531
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7852531
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-020-01113-y
