Deficiency of Wiskott–Aldrich syndrome protein has opposing effect on the pro-oncogenic pathway acti...
Deficiency of Wiskott–Aldrich syndrome protein has opposing effect on the pro-oncogenic pathway activation in nonmalignant versus malignant lymphocytes
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Immunodeficiency is associated with cancer risk. Accordingly, hematolymphoid cancers develop in Wiskott–Aldrich syndrome (WAS), an X-linked primary immunodeficiency disorder (PID) resulting from the deficiency of WAS-protein (WASp) expressed predominantly in the hematolymphoid cell lineages. Despite the correlation between WASp deficiency and hemat...
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Full title
Deficiency of Wiskott–Aldrich syndrome protein has opposing effect on the pro-oncogenic pathway activation in nonmalignant versus malignant lymphocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7855887
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7855887
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-01533-3