Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition...
Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Merkel cell carcinoma (MCC) is a highly invasive and metastatic skin cancer. While high expression of miR-375 is a characteristic of MCC, it seems not to contribute to the malignant phenotype of MCC cells. miR-375 enrichment in MCC-derived extracellular vesicles suggests its intercellular signaling function. Here, we demonstrate that horizontally t...
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Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7862059
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7862059
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-01576-6
