Use of human peripheral blood mononuclear cells to define immunological properties of nucleic acid n...
Use of human peripheral blood mononuclear cells to define immunological properties of nucleic acid nanoparticles
About this item
Full title
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
This protocol assesses proinflammatory properties of nucleic acid nanoparticles (NANPs) using a validated preclinical model, peripheral blood mononuclear cells (PBMCs), that is highly predictive of cytokine responses. The experimental procedure details the preparation of pyrogen-free NANPs, isolation of PBMCs from freshly collected human blood, and...
Alternative Titles
Full title
Use of human peripheral blood mononuclear cells to define immunological properties of nucleic acid nanoparticles
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7875514
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7875514
Other Identifiers
ISSN
1754-2189,1750-2799
E-ISSN
1750-2799
DOI
10.1038/s41596-020-0393-6
