Immune receptor inhibition through enforced phosphatase recruitment
Immune receptor inhibition through enforced phosphatase recruitment
About this item
Full title
Author / Creator
Fernandes, Ricardo A. , Su, Leon , Nishiga, Yoko , Ren, Junming , Bhuiyan, Aladdin M. , Cheng, Ning , Kuo, Calvin J. , Picton, Lora K. , Ohtsuki, Shozo , Majzner, Robbie G. , Rietberg, Skyler P. , Mackall, Crystal L. , Yin, Qian , Ali, Lestat R. , Yang, Xinbo , Savvides, Christina S. , Sage, Julien , Dougan, Michael and Garcia, K. Christopher
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Antibodies that antagonize extracellular receptor–ligand interactions are used as therapeutic agents for many diseases to inhibit signalling by cell-surface receptors
1
. However, this approach does not directly prevent intracellular signalling, such as through tonic or sustained signalling after ligand engagement. Here we present an alternat...
Alternative Titles
Full title
Immune receptor inhibition through enforced phosphatase recruitment
Authors, Artists and Contributors
Author / Creator
Su, Leon
Nishiga, Yoko
Ren, Junming
Bhuiyan, Aladdin M.
Cheng, Ning
Kuo, Calvin J.
Picton, Lora K.
Ohtsuki, Shozo
Majzner, Robbie G.
Rietberg, Skyler P.
Mackall, Crystal L.
Yin, Qian
Ali, Lestat R.
Yang, Xinbo
Savvides, Christina S.
Sage, Julien
Dougan, Michael
Garcia, K. Christopher
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7875542
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7875542
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2851-2
