Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchy...
Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype
About this item
Full title
Author / Creator
Ciardiello, Davide , Blauensteiner, Bernadette , Matrone, Nunzia , Belli, Valentina , Mohr, Thomas , Vitiello, Pietro Paolo , Martini, Giulia , Poliero, Luca , Cardone, Claudia , Napolitano, Stefania , De Falco, Vincenzo , Giunta, Emilio Francesco , Ciaramella, Vincenza , Corte, Carminia della , Barra, Giusi , Selvaggi, Francesco , Franco, Renato , Marino, Federica Zito , Cuomo, Antonio , Morgillo, Floriana , Troiani, Teresa , Sibilia, Maria , Ciardiello, Fortunato and Martinelli, Erika
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
A subset of colorectal cancer (CRC) with a mesenchymal phenotype (CMS4) displays an aggressive disease, with an increased risk of recurrence after surgery, reduced survival, and resistance to standard treatments. It has been shown that the AXL and TGFβ signaling pathways are involved in epithelial-to-mesenchymal transition, migration, metastatic sp...
Alternative Titles
Full title
Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype
Authors, Artists and Contributors
Author / Creator
Blauensteiner, Bernadette
Matrone, Nunzia
Belli, Valentina
Mohr, Thomas
Vitiello, Pietro Paolo
Martini, Giulia
Poliero, Luca
Cardone, Claudia
Napolitano, Stefania
De Falco, Vincenzo
Giunta, Emilio Francesco
Ciaramella, Vincenza
Corte, Carminia della
Barra, Giusi
Selvaggi, Francesco
Franco, Renato
Marino, Federica Zito
Cuomo, Antonio
Morgillo, Floriana
Troiani, Teresa
Sibilia, Maria
Ciardiello, Fortunato
Martinelli, Erika
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7878213
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7878213
Other Identifiers
ISSN
1357-0560
E-ISSN
1559-131X
DOI
10.1007/s12032-021-01464-3
