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Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine

Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7880238

Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine

About this item

Full title

Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Drug discovery, 2020-07, Vol.19 (7), p.480-494

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The Hippo pathway is an evolutionarily conserved signalling pathway with key roles in organ development, epithelial homeostasis, tissue regeneration, wound healing and immune modulation. Many of these roles are mediated by the transcriptional effectors YAP and TAZ, which direct gene expression via control of the TEAD family of transcription factors...

Alternative Titles

Full title

Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7880238

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7880238

Other Identifiers

ISSN

1474-1776

E-ISSN

1474-1784

DOI

10.1038/s41573-020-0070-z

How to access this item