Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epider...
Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epidermis
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Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
With age, the epidermis becomes hypoplastic and hypoproliferative. Hypoproliferation due to aging has been associated with decreased stem cell (SC) self‐renewal in multiple murine tissues. The fate of SC self‐renewal divisions can be asymmetric (one SC, one committed progenitor) or symmetric (two SCs). Increased asymmetric SC self‐renewal has been...
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Full title
Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epidermis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7884041
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7884041
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.13310
