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Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioava...

Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioava...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7899691

Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioavailability and attenuated cardiac ischemia/reperfusion injury in mice

About this item

Full title

Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioavailability and attenuated cardiac ischemia/reperfusion injury in mice

Publisher

England: Taylor & Francis

Journal title

Drug delivery, 2021-01, Vol.28 (1), p.433-444

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

Nicotinamide riboside (NR), as a dietary supplement, can be converted to nicotinamide adenine dinucleotide (NAD
+
) in cells to support mitochondrial energy metabolism. However, the efficacy of oral administrated NR is limited due to its quick degradation in circulation and low bioavailability in targeted organs. In this study, we fabricated...

Alternative Titles

Full title

Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioavailability and attenuated cardiac ischemia/reperfusion injury in mice

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7899691

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7899691

Other Identifiers

ISSN

1071-7544

E-ISSN

1521-0464

DOI

10.1080/10717544.2021.1886198

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