Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioava...
Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioavailability and attenuated cardiac ischemia/reperfusion injury in mice
About this item
Full title
Author / Creator
Nie, Hongfei , Zhang, Yarong , Yu, Haiyang , Xiao, Hong , Li, Tao and Yang, Qian
Publisher
England: Taylor & Francis
Journal title
Language
English
Formats
Publication information
Publisher
England: Taylor & Francis
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Scope and Contents
Contents
Nicotinamide riboside (NR), as a dietary supplement, can be converted to nicotinamide adenine dinucleotide (NAD
+
) in cells to support mitochondrial energy metabolism. However, the efficacy of oral administrated NR is limited due to its quick degradation in circulation and low bioavailability in targeted organs. In this study, we fabricated...
Alternative Titles
Full title
Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD+ bioavailability and attenuated cardiac ischemia/reperfusion injury in mice
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7899691
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7899691
Other Identifiers
ISSN
1071-7544
E-ISSN
1521-0464
DOI
10.1080/10717544.2021.1886198