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γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis

γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7906917

γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis

About this item

Full title

γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2021-03, Vol.22 (3), p.347-357

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Activated Vγ9Vδ2 (γδ2) T lymphocytes that sense parasite-produced phosphoantigens are expanded in
Plasmodium falciparum–
infected patients. Although previous studies suggested that γδ2 T cells help control erythrocytic malaria, whether γδ2 T cells recognize infected red blood cells (iRBCs) was uncertain. Here we show that iRBCs stained for th...

Alternative Titles

Full title

γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7906917

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7906917

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-020-00847-4

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