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Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib

Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7935771

Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib

About this item

Full title

Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib

Publisher

Cham: Springer International Publishing

Journal title

Clinical pharmacokinetics, 2021-03, Vol.60 (3), p.283-303

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Selumetinib, a highly specific mitogen-activated protein kinase 1/2 inhibitor, is approved for children older than 2 years of age with neurofibromatosis 1 who have inoperable plexiform neurofibromas. By selectively binding to mitogen-activated protein kinase 1/2 proteins, selumetinib can arrest the mitogen-activated protein kinase/extracellular sig...

Alternative Titles

Full title

Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7935771

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7935771

Other Identifiers

ISSN

0312-5963,1179-1926

E-ISSN

1179-1926

DOI

10.1007/s40262-020-00967-y

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