Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted ther...
Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation
About this item
Full title
Author / Creator
Lee, Sang-Hyun , Kim, Jin-Man , Lee, Dong Gwang , Lee, Jangwook , Park, Jong-Gil , Han, Tae-Su , Cho, Hyun-Soo , Cho, Young-Lai , Bae, Kwang-Hee , Park, Young-Jun , Lee, Seon-Jin , Lee, Moo-Seung , Huh, Yong-Min , Jo, Deog Yeon , Yun, Hwan-Jung , Jeon, Heung Jin , Kim, Nayoung , Joo, Mina , Kim, Jang-Seong , Lee, Hyo Jin and Min, Jeong-Ki
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Gallbladder carcinoma (GBC) exhibits poor prognosis due to local recurrence, metastasis, and resistance to targeted therapies. Using clinicopathological analyses of GBC patients along with molecular in vitro and tumor in vivo analysis of GBC cells, we showed that reduction of Dsg2 expression was highly associated with higher T stage, more perineura...
Alternative Titles
Full title
Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7937683
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7937683
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-020-00628-4
