Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
About this item
Full title
Author / Creator
Gordon, Anthony C , Mouncey, Paul R , Al-Beidh, Farah , Rowan, Kathryn M , Nichol, Alistair D , Arabi, Yaseen M , Annane, Djillali , Beane, Abi , van Bentum-Puijk, Wilma , Berry, Lindsay R , Bhimani, Zahra , Bonten, Marc J M , Bradbury, Charlotte A , Brunkhorst, Frank M , Buzgau, Adrian , Cheng, Allen C , Detry, Michelle A , Duffy, Eamon J , Estcourt, Lise J , Fitzgerald, Mark , Goossens, Herman , Haniffa, Rashan , Higgins, Alisa M , Hills, Thomas E , Horvat, Christopher M , Lamontagne, Francois , Lawler, Patrick R , Leavis, Helen L , Linstrum, Kelsey M , Litton, Edward , Lorenzi, Elizabeth , Marshall, John C , Mayr, Florian B , McAuley, Daniel F , McGlothlin, Anna , McGuinness, Shay P , McVerry, Bryan J , Montgomery, Stephanie K , Morpeth, Susan C , Murthy, Srinivas , Orr, Katrina , Parke, Rachael L , Parker, Jane C , Patanwala, Asad E , Pettilä, Ville , Rademaker, Emma , Santos, Marlene S , Saunders, Christina T , Seymour, Christopher W , Shankar-Hari, Manu , Sligl, Wendy I , Turgeon, Alexis F , Turner, Anne M , van de Veerdonk, Frank L , Zarychanski, Ryan , Green, Cameron , Lewis, Roger J , Angus, Derek C , McArthur, Colin J , Berry, Scott , Webb, Steve A , Derde, Lennie P G , The REMAP-CAP Investigators and REMAP-CAP Investigators
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
The interleukin-6 receptor blockers tocilizumab and sarilumab were tested against standard care in a randomized trial involving patients newly admitted to the intensive care unit and requiring respiratory or blood-pressure support. The median number of organ support–free days was 10 with tocilizumab, 11 with sarilumab, and 0 with standard care.
Alternative Titles
Full title
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
Authors, Artists and Contributors
Author / Creator
Mouncey, Paul R
Al-Beidh, Farah
Rowan, Kathryn M
Nichol, Alistair D
Arabi, Yaseen M
Annane, Djillali
Beane, Abi
van Bentum-Puijk, Wilma
Berry, Lindsay R
Bhimani, Zahra
Bonten, Marc J M
Bradbury, Charlotte A
Brunkhorst, Frank M
Buzgau, Adrian
Cheng, Allen C
Detry, Michelle A
Duffy, Eamon J
Estcourt, Lise J
Fitzgerald, Mark
Goossens, Herman
Haniffa, Rashan
Higgins, Alisa M
Hills, Thomas E
Horvat, Christopher M
Lamontagne, Francois
Lawler, Patrick R
Leavis, Helen L
Linstrum, Kelsey M
Litton, Edward
Lorenzi, Elizabeth
Marshall, John C
Mayr, Florian B
McAuley, Daniel F
McGlothlin, Anna
McGuinness, Shay P
McVerry, Bryan J
Montgomery, Stephanie K
Morpeth, Susan C
Murthy, Srinivas
Orr, Katrina
Parke, Rachael L
Parker, Jane C
Patanwala, Asad E
Pettilä, Ville
Rademaker, Emma
Santos, Marlene S
Saunders, Christina T
Seymour, Christopher W
Shankar-Hari, Manu
Sligl, Wendy I
Turgeon, Alexis F
Turner, Anne M
van de Veerdonk, Frank L
Zarychanski, Ryan
Green, Cameron
Lewis, Roger J
Angus, Derek C
McArthur, Colin J
Berry, Scott
Webb, Steve A
Derde, Lennie P G
The REMAP-CAP Investigators
REMAP-CAP Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7953461
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7953461
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2100433
