Molecular goniometers for single-particle cryo-electron microscopy of DNA-binding proteins
Molecular goniometers for single-particle cryo-electron microscopy of DNA-binding proteins
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Correct reconstruction of macromolecular structure by cryo-electron microscopy (cryo-EM) relies on accurate determination of the orientation of single-particle images. For small (<100 kDa) DNA-binding proteins, obtaining particle images with sufficiently asymmetric features to correctly guide alignment is challenging. We apply DNA origami to constr...
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Full title
Molecular goniometers for single-particle cryo-electron microscopy of DNA-binding proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7956247
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7956247
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-020-0716-8
