STING controls nociception via type I interferon signalling in sensory neurons
STING controls nociception via type I interferon signalling in sensory neurons
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The innate immune regulator STING is a critical sensor of self- and pathogen-derived DNA. DNA sensing by STING leads to the induction of type-I interferons (IFN-I) and other cytokines, which promote immune-cell-mediated eradication of pathogens and neoplastic cells
1
,
2
. STING is also a robust driver of antitumour immunity, which has...
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Full title
STING controls nociception via type I interferon signalling in sensory neurons
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7977781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7977781
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-03151-1