SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
About this item
Full title
Author / Creator
Wahl, Angela , Gralinski, Lisa E. , Johnson, Claire E. , Yao, Wenbo , Kovarova, Martina , Dinnon, Kenneth H. , Liu, Hongwei , Madden, Victoria J. , Krzystek, Halina M. , De, Chandrav , White, Kristen K. , Gully, Kendra , Schäfer, Alexandra , Zaman, Tanzila , Leist, Sarah R. , Grant, Paul O. , Bluemling, Gregory R. , Kolykhalov, Alexander A. , Natchus, Michael G. , Askin, Frederic B. , Painter, George , Browne, Edward P. , Jones, Corbin D. , Pickles, Raymond J. , Baric, Ralph S. and Garcia, J. Victor
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
All coronaviruses known to have recently emerged as human pathogens probably originated in bats
1
. Here we use a single experimental platform based on immunodeficient mice implanted with human lung tissue (hereafter, human lung-only mice (LoM)) to demonstrate the efficient in vivo replication of severe acute respiratory syndrome coronavirus...
Alternative Titles
Full title
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
Authors, Artists and Contributors
Author / Creator
Gralinski, Lisa E.
Johnson, Claire E.
Yao, Wenbo
Kovarova, Martina
Dinnon, Kenneth H.
Liu, Hongwei
Madden, Victoria J.
Krzystek, Halina M.
De, Chandrav
White, Kristen K.
Gully, Kendra
Schäfer, Alexandra
Zaman, Tanzila
Leist, Sarah R.
Grant, Paul O.
Bluemling, Gregory R.
Kolykhalov, Alexander A.
Natchus, Michael G.
Askin, Frederic B.
Painter, George
Browne, Edward P.
Jones, Corbin D.
Pickles, Raymond J.
Baric, Ralph S.
Garcia, J. Victor
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7979515
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7979515
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03312-w