Blocking elevated p38 MAPK restores efferocytosis and inflammatory resolution in the elderly
Blocking elevated p38 MAPK restores efferocytosis and inflammatory resolution in the elderly
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Increasing age alters innate immune–mediated responses; however, the mechanisms underpinning these changes in humans are not fully understood. Using a human dermal model of acute inflammation, we found that, although inflammatory onset is similar between young and elderly individuals, the resolution phase was substantially impaired in elderly indiv...
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Full title
Blocking elevated p38 MAPK restores efferocytosis and inflammatory resolution in the elderly
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7983074
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7983074
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-020-0646-0
